This native Denver quartet leaped into the big leagues when it composed the poignant score for Little Miss Sunshine. While the film went on to Oscar glory, the band’s multi-instrumental soundtrack—featuring its cadre of guitars, piano, violin, and accordion among others—earned a Grammy nomination. The group’s latest release was recorded live with a full, 60-piece orchestra from the Colorado Symphony serving as the back-up band on grandiose, rock-meets-classical tracks. The show doubles as a benefit for the Bonfils Blood Center. Thu 8 p.m.