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Best CBD Vape Pen in 2022 – Top 5 Best Disposable & Refillable CBD Vapes

Finding the best CBD vape pens when you’re bombarded with brightly colored packaging and tons of brands you may not have heard of can make it difficult to make a decision. Choice overload is real, especially when it comes to CBD vape pens. You can pick between disposables, refillables, and then there are the CBD vape juice flavors! It’s a lot but to keep you focused, we narrowed our list of best CBD vape pens down to five brands.

These brands are reputable, and they’ve created some fantastic options for you. We give you the skinny on each company, break down their vape pen offerings, and share some customer reviews. We also explain the difference between disposables and refillables and highlight the benefits and potential side effects of vaping CBD. At the end of this article, we answer some of your most commonly asked questions, so you have all the information you need in one place.

Top 5 CBD Vape Pens

  1. CBDfx – Best Choice in CBD Vape Pen
  2. Diamond CBD: – Great Variety
  3. CBD American Shaman – Adjustable Battery
  4. Koi CBD – Full-Spectrum Vape
  5. Extract Labs – Great Flavors

Best CBD Vape Pens

1. CBDfx – Best Choice in CBD Vape Pen


  • Save up to 25% with code “chill”
  • CO2 extracted CBD
  • Broad-spectrum CBD
  • Wide variety of CBD vape pens to choose from


  • None

A Peek into the Company

CBDfx was founded in 2014 and has become a CBD industry leader – including their CBD vape pens. They’ve designed a line of CBD vapes that are each discreet and easy to carry with you wherever you go. They grow their organic hemp in the U.S. and use the cleanest extraction method available so you can enjoy products without any residual solvents or other contaminants. They’ve recently upgraded the design of their CBD vape pens, making them slightly larger, with a higher potency, more best-selling flavors, and they’re now rechargeable/disposable!

About the CBD Vape Pens

You have a total of nine rechargeable or disposable vape pens to select from, each with a different CBD formula and mouth-watering flavor. If you’re looking for a good nighttime vape, check out the Purple Punch indica vape pen—it contains delta-9 THC along with CBD and CBN for the ultimate relaxing effects. That’s a total of 500 mg of full-spectrum CBD, 5 mg of THC, and 30 mg of CBN per pen.

For a daytime option that keeps you up and at ‘em, try the Maui Wowie sativa CBD vape pen. This one contains 500 mg of full-spectrum CBD, 5 mg of sativa THC, and comes with a warning that it may cause a psychotropic effect. There are approximately 800 puffs per disposable vape pen and the ceramic coil has a 2mL capacity.

There is a hybrid option that is well-known—the Pineapple Express strain, which gives you the unmistakable uplifting vibe of a strong sativa strain with some of the relaxing benefits of an indica strain. This one also comes with a warning for psychotropic effects. It contains 500 mg of full-spectrum CBD, 5 mg of hybrid THC, and you can dispose of it or recharge it as needed!

Another hybrid option is the Wedding Cake CBD vape pen. It contains delta-9 THC along with CBD. Each pen is loaded with 500 mg of full-spectrum CBD, 5 mg of hybrid THC, and contains a total of two grams. With this strain, you get the feel-good effects of sativa along with the calm-inducing effects of an indica. Kick your feet up in your backyard, enjoy the fresh air, and add more chill to your afternoon vibe.

Take it back to the old school days with the OG Kush vape pen. This one combines CBD with delta-9 THC, delivering all the delicious effects of an indica strain with legal levels of THC. This is a highly revered strain that delivers a strong herbaceous flavor that offers the smoothest hits you’ve ever had—every time you take a puff.

For expertly crafted, fruity flavor, you have to check out the Blue Raspberry CBD vape pen. It contains 500 mg of broad-spectrum CBD, so you don’t have to worry about any THC content if that’s a concern for you. The flavor is ultra-rich, and the pen contains only all-natural ingredients with the ideal 50/50 PG and VG ratio, which affords you the perfect puff each time you reach for it.

The Strawberry Lemonade CBD vape pen is another fruity flavor with a slightly sour spin. It contains 500 mg of broad-spectrum CBD and serves as a tangy treat that helps you chill out whenever you need some relief from the day’s troubles. There are no buttons to push and it’s easy to recharge with a micro USB (not included).

The Tropic Breeze CBD vape pen contains 500 mg of broad-spectrum CBD and delivers approximately 800 puffs total. The flavor is rich and fruity and contains only all-natural ingredients with a 50/50 PG and VG ratio. The final option is the Fresh Mint CBD vape pen, which is perfect if you love that minty, refreshing flavor. It contains 500 mg of organic, broad-spectrum CBD.

CBDfx also offers a great starter CBD vape kit with a ceramic coil, USB charger and one-button, straight-forward operation. Buy the kit and you get 10% off one of CBDfx’s vape juices – nice deal!

What Customers Love

Customers comment on the way these CBD vape pens taste. The hits are smooth, and the effects are incredibly calming. Those that choose an indica strain comment that their sleep has improved. One customer credits the Purple Punch vape pen for taking the sharp edge off the neurological pain he experiences. She always keeps a charged vape pen with her.

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2. Diamond CBD – Great Variety


  • Subscribe to save 30%
  • Organically grown hemp
  • GMO and synthetics-free
  • Trade your email for exclusive discounts


  • Unless you subscribe, you are required to spend at least $100 to qualify for free shipping

A Peek into the Company

Diamond CBD is a research-intensive CBD company that offers a wide range of CBD products, including CBD vape pens. Their products are made in the U.S. from American-grown hemp. They utilize a team of scientists who produce hemp cannabinoids—anything from CBD to delta-8 THC. They even have an award-winning CBD oil that was crafted through very careful research and development. They approach hemp growth in a sustainable way to ensure that they leave the environment better than how they found it. They often offer promotions, helping both new and returning customers save on their purchases. Plus, every time you shop at Diamond CBD, you earn reward points.

About the CBD Vape Pens

Diamond CBD has a large selection of CBD vape pens, both cartridges that require a separate battery and disposables. You can look through three pages on their website to discover the different strains, potencies, and flavors. To give you an idea of what you can expect, we highlight a few of their best sellers below.

The Green Crack cartridge by Chill Plus delivers that potent, energizing vibe that sativa lovers crave. The flavor is tangy and fruity and makes for the perfect daytime vape. Keep your spirits up, even when the day is gray—Green Crack is all about that fun, floaty feeling that takes your worries away. It contains 900 mg of Delta-8 THC per cartridge. Just make sure you pick up a 510-compatible battery.

They also offer Blue Dream disposable CBD vape pens by Raw Cannabinoid that contain 800 mg of active CBD. These types of CBD vape pens are made with a proprietary blend of all-natural, hemp-derived cannabinoids. If you’re not familiar with Blue Dream, it’s a must-try strain. It has an herbaceous flavor with notes of pine. It’s the type of CBD strain that blisses you out, giving you the mood boost you need to tackle anything.

Raw Cannabinoid has a variety of CBD vape pens to choose from, including Pineapple Express. This disposable CBD vape pen arrives ready to use. It contains 800 mg of CBD. The flavor of this strain is sweet with notes of pineapple, apple, and cedar. This is a hybrid that combines the Trainwreck and Hawaiian strains to create a pleasurable, soothing experience with each puff.

If you’re into indica strains, check out the Grape Ape disposable CBD vape pen. It contains 800 mg of CBD and it’s packed with mostly indica strains like Mendocino Purps, Afghani, and Skunk. When you need to relax, wind down, and let the stress of the day melt away, this is the perfect go-to CBD vape pen. With any of these disposable CBD vape pens, you can choose to subscribe to save 20% off and enjoy free shipping with every order!

What Customers Love

Customers love the selection of disposable and refillable CBD vape pens on the Diamond CBD website. They each have their favorites for different reasons, but the general sentiment is that these strains will have you on cloud nine all day. They describe the hits as smooth with strong, pleasant flavors. One verified buyer sticks with Green Crack and says it keeps her happy and motivated to get things done.

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3. CBD American Shaman – Adjustable Battery


  • 100% satisfaction guarantee
  • Gluten-free and eco-friendly CBD
  • Proprietary nanotechnology
  • Adjustable CBD vape pen


  • This product may sell out due to high demand; however, you can always place your order on backorder

A Peek into the Company

CBD American Shaman selects only the highest-grade hemp plants grown on agriculturally responsible farms in the U.S. They are certified by the U.S. Hemp Authority, which means they follow industry standards when it comes to product safety and quality. Their mission is simple: to deliver wellness products to their customer base using the best CBD on the market. Their CBD products are made with proprietary nanotechnology that shrinks CBD particles to make them more bioavailable.

About the CBD Vape Pens

CBD American Shaman offers the Exxus Twistr vape pen that has an adjustable temperature setting that goes from 1.0V to 4.0V. It’s equipped with a single button that can activate two settings for a 10-second preheat. Click the button twice to activate the preheat and one to stop the preheat. The battery comes with a USB charger and so long as you register the product, you can enjoy a lifetime warranty.</span

What Customers Love

Customers love that this vape pen combines two of the best vape pen advancements. On the one hand, the timed preheating cycle, and on the other, the adjustable power. They find that it’s really accurate and intuitive and they love that it’s surprisingly inexpensive.

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4. Koi CBD – Full-Spectrum Vape


  • Save 15% on your first order
  • Full-spectrum hemp extract
  • Subscribe to save 20%
  • Third-party lab tested


  • Not all products have current COAs available

A Peek into the Company

Koi CBD is part of the California Hemp Council and U.S. Hemp Roundtable Board of Directors. They set out to create a higher standard of quality for CBD users. They employ a strict validation process for all their vendors to ensure they only ever use the best hemp extract available. All of their hemp is grown and extracted in the U.S., which is ultimately what empowers them to deliver consistent CBD products their customers love. They offer full traceability from start to finish—that means from farm to distribution. They want you to know and trust their products, so they can win your loyalty.

About the CBD Vape Pens

Koi CBD offers a full-spectrum disposable vape pen with the hybrid strain, Hawaiian Driver. This CBD vape pen combines hemp’s many beneficial compounds, including CBD, THC, and minor cannabinoids. This is a rechargeable disposable CBD vape pen that features a high-grade ceramic coil and a preheating function. Together, these make for the smoothest draws. This is the perfect strain to help you return to center when it feels like the day has gotten away from you. Keep it charged and on hand to experience rapid relief no matter where you are.

What Customers Love

First-time customers are already planning their next purchase from Koi CBD. They love the flavor and calming feeling this disposable CBD vape pen affords them. One customer describes it as “an uplifting experience of relaxation.” The effects are both immediate and noticeable. Another long-term customer praises Koi CBD for crafting the best flavors while always keeping consistent with their high standards.

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5. Extract Labs – Great Flavors


  • Veteran-owned company
  • Certified organic ingredients
  • Manufactured in a cGMP facility
  • Batch tracked from plant to product


  • None

A Peek into the Company

Extract Labs was founded by a combat veteran who had a growing interest in cannabis for medicinal uses. He set out on his mission from his garage and managed to turn his project into a full-scale CBD company that has gained a positive reputation for its dedication to improving the quality of life for others through proper research, development, and manufacturing of the highest quality CBD products possible. Extract Labs has partnered with CSU to help fund research and keep innovating with CBD products that support the overall health and wellness of their customers. Additionally, Extract Labs recognizes that some people may not have the funds to invest in these natural, medicinal products so they’ve developed several discount programs to help those in need of a helping hand.

About the CBD Vape Pens

Extract Labs has a line of CBD vape pen cartridges. They call these CBD vape pens “extract tanks”. You can choose between several strains, including Martian Candy, Garlic Jam, Clementine, Blue Dream, Apple Fritter, El Jefe, God’s Gift, and Guava Jam. Each cartridge contains either 500 mg or 1000 mg of full-spectrum CBD.

If you don’t already have a battery for a new cartridge, you can pick one up directly on the Extract Labs along with your cartridge purchase. The CBD vape kit contains an Extract Labs branded battery that says, “Elevate Yourself” and comes with a USB charger to keep your favorite disposable CBD vape pens ready.

If you’re over disposable CBD vape pens and want to invest in a sleek, high-capacity battery for your 510 thread cartridges, you have to take a look at the new Compass Series by Vessel. This small device fits perfectly in the palm of your hand but packs a powerful punch. It’s designed elegantly and features an unparalleled ergonomic design and Vessel’s signature tuned airflow.

For a refined battery, the Craftsman Series by Vessel takes on a gunmetal and areal walnut wood design that makes each piece unique. It fits most 510 thread cartridges, including Extract Labs’ extract tanks.

What Customers Love

Customers love the quality of the extract tanks. For one customer who deals with anxiety, the El Jefe strain delivers powerful relief. It quickly became his favorite. After the first try, he noticed that his anxiety was completely alleviated. He has become a loyal customer since.

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Factors Used to Create Our Best CBD Vape Pen List

Like with any product, there are some outright dangerous options that might have pretty packaging but that are filled with sketchy ingredients and there are high-quality options you can trust. To ensure we only recommend the best of the best, we took a look at a couple of factors that affect the quality of CBD vape pens. We explain them below.


It all starts with where the hemp cannabis plants are grown. We look for brands that practice organic, sustainable farming without any GMOs, pesticides, or other harmful chemicals. If a brand doesn’t get this first step right, they’re likely to make mistakes along the way, and we simply can’t trust their products. Each of the brands we listed above is doing it right and offering transparency so their customers can be privy to their processes and feel a sense of security when investing their hard-earned dollars into their products.


The extraction method manufacturers use to make the CBD vape oil is important as well. We chose companies that focus on a clean extraction process, like using carbon dioxide to extract their CBD oil from the hemp plant. This is called CO2 extraction. With this form of extraction, you are getting the cleanest possible form of CBD. It leaves out harmful solvents and chemicals, which are often included when a company opts for a cheaper extraction process. We are looking for high-quality products that offer not just a load of tantalizing flavors, but that are safe for you and anyone you share your CBD vape pen with.


We love companies that use organic hemp and that keep their ingredient list simple. These products don’t require a long list of ingredients you can’t even pronounce. Instead, we chose companies that are straightforward and transparent, only including what’s absolutely necessary in their CBD vape pens. There’s no point in fillers unless the manufacturer is trying to cut corners and increase profits in an unethical, dishonest way. It’s unfortunate but it’s a reality. We made sure to only highlight companies that value their customer base and their own reputation—companies that are in it for the long run and work hard to earn their customers’ loyalty.

Third-Party Lab Testing

The Federal Food & Drug Administration does not regulate CBD products. That makes the CBD industry kind of a free-for-all, to each their own type of market. However, brands have the opportunity (and frankly, responsibility) to set up their own third-party tests to keep themselves accountable. This is not a requirement, but it does demonstrate that these CBD companies are committed to integrity in their dealings, ensuring all their products align with their promises. If you see a brand that doesn’t make their Certificate of Analysis and lab reports readily available, be careful. Without proper regulations and checks in place, CBD suppliers can fool you with attractive packaging and marketing. We made sure to double and triple-check that all the companies highlighted above have done their due diligence and offer their customers the transparency they need to know they are purchasing an honest product.

Disposable CBD Vape Pen vs. a Refillable CBD Vape Pen

There are two primary types of vape pens. The disposable CBD vape pens are just that—they serve during the life of the CBD vape juice and then you can toss them out! These are a great option for people who are interested in vaping CBD but are not ready to commit to a refillable CBD vape pen and all that entails. Disposable CBD vape pens are also more cost-effective upfront and require zero maintenance. They’re ready to use upon arrival and once you’re done with it, you can move on to another one.

Refillable CBD vape pens require more care. These types of CBD vape pens require you to change out the CBD vape juice. You can try different types of CBD vape oil cartridges with a refillable CBD vape pen. You are also responsible for cleaning these types of vape pens regularly, including changing out the coil regularly. These are fun because you can easily switch out the CBD vape juice—if you’re craving something fruity at night but prefer something minty in the morning, just switch out the CBD vape juice while you keep using your CBD vape kit.

Note, though, that you cannot vape CBD oil that comes in a bottle because it is not meant to vaporize. Vaping CBD oil can actually be dangerous.

How to Choose a CBD Vape Pen?

You have a solid list of brands and products to choose from but how do you narrow it down? Below, we identify what you should consider before making your final decision.

CBD Type

There are three types of CBD that you can explore. Full-spectrum CBD includes all minor cannabinoids, including THC, which makes it a more well-rounded and potent CBD vape pen. When all cannabinoids are present, they can work together in a complementary way to deliver stronger effects. If you prefer a CBD vape pen without THC, then be sure to look for either broad-spectrum CBD or a CBD isolate vape pen. Broad-spectrum includes minor cannabinoids but leaves out THC. CBD isolate leaves out all other minor cannabinoids and gives you a pure CBD product.

Strain of Hemp Used

There are indica strains, sativa strains, and hybrid strains. Indica strains are preferred by those seeking out a deep sense of relaxation—these are often called nighttime strains because they help you unwind and prepare your mind and body for proper rest. Sativa strains are known as daytime strains because they provide you with an uplifted move and deliver a burst of energy that helps you tackle the tasks of your day in a good mood. Hybrid strains give you a little bit of both worlds, helping you keep a pep in your step with a calm and centered mind that allows you to focus and maintain an elevated mood.

Potency of CBD and Other Cannabinoids

Potency is another important consideration. When you’re deciding on a full-spectrum strain, you’ll notice that the CBD content isn’t the only one identified. You may see that there is a legal amount of THC included along with other minor cannabinoids like CBN or CBG to either help induce a sleepy state or help keep you awake. Understanding the potency of your vape pen along with the strain and type helps ensure you get the right kind for your needs.

Flavor of the CBD Vape Juice

This one might go without saying but you should remember that the other items listed above are of greater importance. An attractive flavor may lure you in but be sure you know about the CBD type, strain, and potency before you take the plunge! The good thing for you is we’ve identified brands that meet our high standards and that offer a wide range of delicious flavors for refillable CBD vape pens and disposable vape pens. If you prefer the earthy, herbaceous terpene flavors, we’ve got you covered. If you’re into tangy, fruity, and sweet flavors, you’ll find them in this list. And if you’re more about a refreshing minty flavor, we’ve got you covered there too!

Price Tag

If you only vape every once in a while, the cost may not be a huge deal to you. Especially since you can usually snag a good deal using coupon codes. However, if you’re serious about vaping CBD juice, you probably have a monthly budget forecast! When that’s the case, it may be more beneficial for you to subscribe for regular deliveries and maximize savings. The brands we highlight are also pretty generous for first-time customers, offering you coupon codes right off the bat. CBDfx is our top favorite because no matter if you’re a first-time customer or a long-term customer, they’re always generous with their coupon codes—that means you can enjoy more for less!

Benefits of CBD

CBD works in myriad ways. Since it interacts with your endocannabinoid system to create balance, it tackles almost any condition or ailment you may be struggling with. You may pick up a CBD vape pen thinking it’ll give you a nice mood boost—and it will—but you may also notice that it relieves any pain you may have been feeling. It could reduce anxiety and anxiety-related behaviors and help improve your sleep cycles as well. CBD is like a gift that keeps on giving. Below, we highlight some of the benefits you could experience when you vape CBD.

Stress Relief

A lot of people vape CBD because it offers stress relief. The day is filled with stressors here and there (like traffic in the morning and evening rush hours) and sometimes, stressors feel like a looming dark cloud that makes you forget what sunlight feels like on your face. CBD can help ease your worries, big and small, and give you some reprieve from the harsh realities you sometimes face.

Overall Wellness

Since CBD communicates directly with your endocannabinoid system, it immediately gets to work in your body to restore homeostasis. You may not even be experiencing any symptoms but still, CBD does what it’s supposed to—keep your body in a balanced state. You can vape CBD or take it in any of its other forms (capsules, oils, topicals) to support your overall wellness year-round.

Better Sleep

You can also vape CBD as part of your nighttime routine to help you wind down and get ready for bed. Indica strains are the most ideal for sleep support because they help you relax—not just your body but also your mind. Keep a disposable CBD vape pen on your nightstand and puff away before bedtime to enjoy a quick descent into sleep and better quality sleep throughout the night.

Improved Mood

The best CBD vape pens are instant mood lifters. They add a floaty feel to your mood that helps you feel uplifted, even when the day is heavy. Some people vape CBD to reduce anxiety, whether it’s chronic or you have an upcoming event that’s giving you that sinking stomach feeling, CBD can help you better manage those feelings and come out on top.

Pain Relief

CBD is also known to provide anti-inflammatory benefits while reducing pain. It’s a natural alternative to over-the-counter and prescription medications, which can sometimes be so potent, that they leave you feeling completely out of it. Additionally, CBD doesn’t have the kind of side effects that sometimes accompany stronger meds but still delivers relief, which makes it a favorite for pain sufferers.

How to Use a CBD Vape Pen?

Some CBD vape pens have a button you need to press before you press the tip to your lips and begin to inhale. Others are powered up by the suction when you start taking a puff. Disposable CBD vape pens are ready to use upon arrival. Just take them out of the packaging and remove any security stickers. You get an approximate number of puffs per vape pen. For example, CBDfx identifies about 800 puffs per vape pen. Use it at your leisure and simply discard it when you’re all done! For new users, you may want to pick up a bundle of different flavors and strains to explore what best suits you.

If you’re using a refillable vape pen, remember that you cannot vape CBD oil made to be ingested. Only buy CBD vape juice or vape oil that’s meant to be vaped.

Side Effects of Vaping

Even the best CBD vape pens may have some side effects. CBD is usually well tolerated but when it comes to vaping CBD, there are some side effects you should know about so you can discontinue use if you notice your body is not taking well to it.

Some people report dry mouth or a dry throat after they vape CBD. One way to help alleviate this symptom is to inhale less at a time and use the vape less frequently. However, some people find this symptom so bothersome they switch over to a different type of CBD product.

There is very little research about the long-term effects of vaping as well. Be sure that you make an informed decision when using any type of CBD vape pen. Although these products have delicious flavors and plenty of benefits, there are also unknown risks when vaping CBD.


What is the best CBD vape pen cartridge?

The best CBD vape pens are by CBDfx. These CBD vapes are designed to give you a memorable experience every time. They come in a wide range of flavors and strains, so no matter what you’re looking for, you’re sure to find it.

Is it best to vape CBD?

Some people enjoy CBD vape oil and CBD vapes because of how fast-acting they are. They don’t need to travel through your digestive system like CBD oil or gummies, so you feel the effects right away. Additionally, some people enjoy CBD vapes because they enjoy the vape oil clouds and the ritual of smoking without any harsh dry herbs.